Motion in Malate Dehydrogenase (MDH) [mdh]

[ jump to morphs ]

Classification Known Fragment Motion, Hinge Mechanism [F-h-2]

4MDH Conformation 1 [ PartsList ]

Comparison of subunits shows a loop closure similar to LDH, moving atom CA atoms up to 8 Angstrom. Motion is evident in comparing different subunits in the asymmetric unit. Single data bank identifier applies for both forms.

Particular values describing motion
Creation Date = 19970822
Modification Date = 19970822
Experimental Methods = x (Traditional x-ray)

J J Birktoft, G Rhodes and L J Banaszak (1989). Refined Crystal Structure of Cytoplasmic Malate Dehydrogenase at 2.5 Å Resolution. Biochemistry. 28: 6065. [Medline info for 93041761]

GO terms associated with structures
Molecular functionL-malate dehydrogenase activity, oxidoreductase activity, L-lactate dehydrogenase activity, malate dehydrogenase activity
Biological processglycolysis, tricarboxylic acid cycle intermediate metabolism, malate metabolism


[ show all images ]
Best representative
Morph Morph name Structure #1 Structure #2 Residues
Via_align 4mdh [ A ] 1bmd [ A ] 327

User-submitted morphs
Morph Morph name Structure #1 Structure #2 Residues
5ldh 5ldh [ A ] 4mdh [ A ] 333

Automatic morphs
Morph Morph name Structure #1 Structure #2 Residues
Malate Dehydrogenase 1ie3 [ D ] 2cmd [ A ] 312

[help] [home] [movies]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_