Motion in T7 DNA Helicasee [t7helicase]

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Classification [S-n-1]

Structures
1e0j
1e0k

Description
See link below.

References
Singleton MR, Sawaya MR, Ellenberger T, Wigley DB (2000). Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides. Cell 101:589-600. [Medline info for 10892646]

Data and Graphics
Wigley Lab Excellent overview of T7 helicase mechanism on Dale Wigley's lab home page. Includes several animations illustrating hypothetical motion in hexamer.

GO terms associated with structures
Molecular functionnucleic acid binding, DNA primase activity
Biological processDNA modification, DNA replication, synthesis of RNA primer


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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu