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Motion in T7 DNA Helicasee [t7helicase]
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Classification [S-n-1]
Structures 1e0j 1e0k
Description See link below.
References Singleton MR, Sawaya MR, Ellenberger T, Wigley DB (2000). Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides. Cell 101:589-600. [Medline info for 10892646]
Data and Graphics Wigley Lab Excellent overview of T7 helicase mechanism on Dale Wigley's lab home page. Includes several animations illustrating hypothetical motion in hexamer.
GO terms associated with structures Molecular function nucleic acid binding, DNA primase activity Biological process DNA replication, synthesis of RNA primer, DNA modification
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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu