Motion in S100 Calcium sensor [s100]

[ jump to morphs ]

Classification [F-s-2]

Structures
1K9P wild-type
1K9K Ca-bound
1K96 Ca-bound (C2 form)
1K8U Ca-free mutant

Description
Similar to calmodulin and troponin; motion involves change in conformation of overall dimer as well as movement in helices.

References
Ludovic R Otterbein, Jolanta Kordowska, Carlos Witte-Hoffmann, C-L Albert Wang, Roberto Dominguez (2002). Crystal Structures of S100A6 in the Ca(2+)-Free and Ca(2+)-Bound States. The Calcium Sensor Mechanism of S100 Proteins Revealed at Atomic Resolution. Structure (Camb), 10:557-67 [Medline info for 11937060]

GO terms associated with structures
Molecular functioncalcium ion binding

Morphs

[ show all images ]
Best representative
Morph Morph name Structure #1 Structure #2 Residues
[ ] [ ]



[help] [home] [movies]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu