Motion in PvuII endonuclease [pvuii]

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Classification [D-s-2]

Structures
1PVU [ PartsList ]
1PVI [ PartsList ]

Description
Motion occurs in the dimer upon binding of DNA. Long helices link monomers, and remain stationary while the larger domains clamp onto the DNA helix. (This motion appears to be a hinged fragment when only one subunit is examined.)

References
A Athanasiadis, M Vlassi, D Kotsifaki, P A Tucker, K S Wilson, M Kokkinidis (1994). Crystal structure of PvuII endonuclease reveals extensive structural homologies to EcoRV. Nat Struct Biol, 1:469-75 [Medline info for 7664066]
X Cheng, K Balendiran, I Schildkraut, J E Anderson (1994). Structure of PvuII endonuclease with cognate DNA. EMBO J, 13:3927-35 [Medline info for 8076590]

Morphs

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Best representative
Morph Morph name Structure #1 Structure #2 Residues
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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu