Motion in DNA Polymerase III [pol3]

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Classification [D-s-2]

Structures 2POL [ PartsList ] 1JQJ

References Kong XP, Onrust R, O'Donnell M, Kuriyan J (1992). Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp. Cell 1992 May 1;69(3):425-37. [Medline info for 1349852] Jeruzalmi D, Yurieva O, Zhao Y, Young M, Stewart J, Hingorani M, O'Donnell M, Kuriyan J (2001). Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell. 2001 Aug 24;106(4):417-28. [Medline info for 11525728]

GO terms associated with structures Molecular function 3'-5' exonuclease activity, delta DNA polymerase activity, DNA binding, DNA-directed DNA polymerase activity Cellular component chromosome Biological process DNA replication

Morphs

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Best representative Morph Morph name Structure #1 Structure #2 Residues Pol III (Beta Subunit) (E.C. 2 2pol [ A ] 1jqj [ A ] 366

User-submitted morphs Morph Morph name Structure #1 Structure #2 Residues 216376-18921 E. coli DNA Polymerase III Sliding Clamp upload [ A ] upload [ A ] 366

Automatic morphs Morph Morph name Structure #1 Structure #2 Residues va1jqjB-2polA DNA Polymerase III, Beta Chain 1jqj [ B ] 2pol [ A ] 366 va1jqjA-1waiA DNA Polymerase III, Beta Chain 1jqj [ A ] 1wai [ A ] 366 va1jqjA-1waiB DNA Polymerase III, Beta Chain 1jqj [ A ] 1wai [ B ] 366 va1jqjB-1waiB DNA Polymerase III, Beta Chain 1jqj [ B ] 1wai [ B ] 366 va1jqjB-2polB DNA Polymerase III, Beta Chain 1jqj [ B ] 2pol [ B ] 366 va1jqjA-2polB DNA Polymerase III, Beta Chain 1jqj [ A ] 2pol [ B ] 366 va1jqlA-2polB DNA Polymerase III, Beta Chain 1jql [ A ] 2pol [ B ] 366

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Email: Mark.Gerstein _at_ yale.edu