Motion in PI-SceI Endonuclease [piscei]

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Classification [C----]

Structures 1VDE [ PartsList ] 1LWT

Description Motion on DNA binding Binding of PI-SceI also induces conformational changes in DNA bound, as descsribed in corresponding paper.

References Carmen M Moure, Frederick S Gimble, Florante A Quiocho (2002). Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence. Nat Struct Biol, 9:764-70 [Medline info for 12219083] X Duan, F S Gimble, F A Quiocho (1997). Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity. Cell, 89:555-64 [Medline info for 9160747]

GO terms associated with structures Molecular function hydrogen-transporting ATP synthase activity, rotational mechanism, hydrogen-transporting ATPase activity, rotational mechanism, DNA binding, endonuclease activity, ATP binding Cellular component proton-transporting two-sector ATPase complex Biological process ATP biosynthesis, ATP synthesis coupled proton transport, intein-mediated protein splicing, protein splicing

Morphs

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Best representative Morph Morph name Structure #1 Structure #2 Residues PI-SceI Endonuclease 1vde [ A ] 1lwt [ A ] 446

User-submitted morphs Morph Morph name Structure #1 Structure #2 Residues 980222-17953 intein with DNA 1vde [ A ] 1lwt [ A ] 446

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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu