Motion in MMLV Reverse Transcriptase [mmlvrt]

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Classification [D-h-2]

Structures 1QAI 1MML [ PartsList ]

References S Najmudin, M L Coté, D Sun, S Yohannan, S P Montano, J Gu, M M Georgiadis (2000). Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain. J Mol Biol, 296:613-32 [Medline info for 10669612] D Sun, S Jessen, C Liu, X Liu, S Najmudin, M M Georgiadis (1998). Cloning, expression, and purification of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase: crystallization of nucleic acid complexes. Protein Sci, 7:1575-82 [Medline info for 9684890] M M Georgiadis, S M Jessen, C M Ogata, A Telesnitsky, S P Goff, W A Hendrickson (1995). Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase. Structure, 3:879-92 [Medline info for 8535782]

GO terms associated with structures Molecular function RNA binding, RNA-directed DNA polymerase activity, aspartic-type endopeptidase activity, nucleic acid binding, ribonuclease H activity, DNA binding Biological process RNA-dependent DNA replication, DNA recombination, proteolysis and peptidolysis

Morphs

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Best representative Morph Morph name Structure #1 Structure #2 Residues [ ] [ ]

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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu