Motion in Lysine/Arginine/Ornithine (LAO) binding protein [lao]

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Classification Known Domain Motion, Hinge Mechanism [D-h-2]

Structures 1LST Conformation 1 [ PartsList ] 2LAO Conformation2 [ PartsList ]

Description 2 interdomain linkages, 2 hinges, 52 degree rotation. In the LAO binding protein there is a 52 degree rotation of the two domains, which involves only a few large torsion angle changes in regions structurally equivalent to the lactoferrin hinges.

Particular values describing motion Creation Date = 19970822 Experimental Methods = x (Traditional x-ray) Modification Date = 1998-06-27 22:03:47.000

References B-H Oh, J Pandit, C-H Kang, K Nikaido, S Gokcen, G F-L Ames and S-H Kim (1993). Three-dimensional structures of the Periplasmic Lysine/Arginine/Ornithine-binding Protein with and without a Ligand. J. Biol. Chem. 268: 11348-11355. [Medline info for 93266593]

GO terms associated with structures Molecular function transporter activity Cellular component periplasmic space (sensu Gram-negative Bacteria) Biological process transport

Morphs

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Best representative Morph Morph name Structure #1 Structure #2 Residues [ ] [ ]

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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu