Motion in Influenza Matrix Protein M1 [impm1]

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Classification [D-h-2]

Structures
1AA7 [ PartsList ]
1EA3

Description
Movie of two structures of the same amino-terminal domain of influenza A virus matrix protein (residues 1-164) crystallized at pH 7 and pH 4 by two seperate groups. Significant changes in protein conformation occur in the areas of protein-protein contacts that are different in the two crystals, expecially in the area where dimer contacts occur in the pH 4 structure (residues 36, 86-94)

References
B Sha, M Luo (1997). Structure of a bifunctional membrane-RNA binding protein, influenza virus matrix protein M1. Nat Struct Biol, 4:239-44 [Medline info for 9164466]
S Arzt, F Baudin, A Barge, P Timmins, W P Burmeister, R W Ruigrok (2001). Combined results from solution studies on intact influenza virus M1 protein and from a new crystal form of its N-terminal domain show that M1 is an elongated monomer. Virology, 279:439-46 [Medline info for 11162800]

GO terms associated with structures
Molecular functionRNA binding, structural molecule activity

Morphs

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Best representative
Morph Morph name Structure #1 Structure #2 Residues
Influenza Virus Matrix Protein M1 1aa7 [ A ] 1ea3 [ A ] 164



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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu