Motion in Influenza Matrix Protein M1 [impm1]
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Classification [D-h-2]
Structures 1AA7 [ PartsList ] 1EA3
Description Movie of two structures of the same amino-terminal domain of influenza A virus matrix protein (residues 1-164) crystallized at pH 7 and pH 4 by two seperate groups. Significant changes in protein conformation occur in the areas of protein-protein contacts that are different in the two crystals, expecially in the area where dimer contacts occur in the pH 4 structure (residues 36, 86-94)
References B Sha, M Luo (1997). Structure of a bifunctional membrane-RNA binding protein, influenza virus matrix protein M1. Nat Struct Biol, 4:239-44 [Medline info for 9164466] S Arzt, F Baudin, A Barge, P Timmins, W P Burmeister, R W Ruigrok (2001). Combined results from solution studies on intact influenza virus M1 protein and from a new crystal form of its N-terminal domain show that M1 is an elongated monomer. Virology, 279:439-46 [Medline info for 11162800]
GO terms associated with structures Molecular function RNA binding, structural molecule activity
Morphs
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Best representative Morph Morph name Structure #1 Structure #2 Residues [ ] [ ]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu