Motion in Heat Shock Transcription Factor [hsf]

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Classification Known Domain Motion, Hinge Mechanism [D-h-2]

3HSF NMR, unbound [ PartsList ]
3HTS X-ray, complex with DNA

Mechanism of contacting DNA is similar to catabolite activator protein (CAP), histone H4, HNF-3/fork-head motif, biotin repressor, and HSF]. In particular, HSF and CAP share a specific sequence of secondary structure elements. However, HSF is only known trimeric DNA binding protein.

Particular values describing motion
Experimental Methods = x (Traditional x-ray)
Creation Date = 19971130
Modification Date = 19971130

C J Harrison, A A Bohm, H C M Nelson. Crystal Structure of the DNA Binding Domain of the Heat Shock Trnascription Factor. Sci. 263:224-227. [Medline info for 93945018]

GO terms associated with structures
Molecular functionDNA binding, transcription factor activity
Cellular componentnucleus
Biological processregulation of transcription, DNA-dependent


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Best representative
Morph Morph name Structure #1 Structure #2 Residues
Heat Shock TF DNA-binding domain upload [ A ] upload [ B ] 81

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Email: Mark.Gerstein _at_