Motion in Heterotrimeric G protein [gprot]

[ jump to morphs ]

Classification Known Domain Motion, Unclassifiable Mechanism [D-?-2]

Structures
1TAG Conformation 1 [ PartsList ]
1GOT Conformation 2 [ PartsList ]

Description
Heterotrimeric G protein has been solved in at least three conformations: Unbound, bound to GTP-gamma S and bound to GTP.

Particular values describing motion
Experimental Methods = x (Traditional x-ray)
Creation Date = 19971130
Modification Date = 19971130

References
D G Lambright, J P Noel, H E Hamm, and P B Sigler (1994). Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein. Nature. 369:621-628. [Medline info for 96365222]
C Branden and J Tooze. Introduction to Protein Structure.

GO terms associated with structures
Molecular functionsignal transducer activity, GTP binding
Biological processG-protein coupled receptor protein signaling pathway, signal transduction


[help] [home] [movies]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu