Motion in Heterotrimeric G protein [gprot]

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Classification Known Domain Motion, Unclassifiable Mechanism [D-?-2]

Structures 1TAG Conformation 1 [ PartsList ] 1GOT Conformation 2 [ PartsList ]

Description Heterotrimeric G protein has been solved in at least three conformations: Unbound, bound to GTP-gamma S and bound to GTP.

Particular values describing motion Experimental Methods = x (Traditional x-ray) Creation Date = 19971130 Modification Date = 19971130

References D G Lambright, J P Noel, H E Hamm, and P B Sigler (1994). Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein. Nature. 369:621-628. [Medline info for 96365222] C Branden and J Tooze. Introduction to Protein Structure.

GO terms associated with structures Molecular function signal transducer activity, GTP binding Biological process signal transduction, G-protein coupled receptor protein signaling pathway

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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu