Motion in Glycerol Kinase [gk]
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Classification Known Domain Motion, Shear Mechanism [D-s-2]
Description Expected to be similar to hexokinase and actin based on structural similarity. However, domain repositioning is accurately described by rigid body motion rather than rearrangement of secondary struture elements. The motion also appears to be directly related to allosteric regulation by the regulator Fructose 1,6-bisphosphate which is a non-competitive inhibitor.
Particular values describing motion Creation Date = 1998-10-23 09:58:31.000 Experimental Methods = x (Traditional x-ray) Maximum Rotation (degrees) = 6.2 Maximum Translation (A) = 0.2 Number of hinges = 1 Modification Date = 1998-11-06 22:13:01.000
Morphs
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Best representative Morph Morph name Structure #1 Structure #2 Residues [ ] [ ]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu