Motion in F1-ATPase [f1atpase]
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Classification Suspected Subunit Motion, Not Involving Allostery [S-n-1]
Description Six globular subunits (3 alpha and 3 beta) are arranged around a long central helix (gamma subunit). Because of the asymmetries in the orientation of the alpha and beta subunits, they are hypothesized to rotate around the central helix. Also comparison of the beta subunits shows that in one of them (beta-E) a sheet has partially unfolded.
Particular values describing motion Experimental Methods = x (Traditional x-ray) Creation Date = 19970822 Modification Date = 19970822
References J P Abrahams, A G W Leslie, R Lutter and J E Walker (1994). Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria. Nature. 370: 621-628. [Medline info for 94344236]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu