Motion in Glutamate Dehydrogenase (GDH) [cdh]

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Classification Known Domain Motion, Hinge Mechanism [D-h-2]

Structures 1GTM Conformation 1 [ PartsList ] 1HRD Conformation 2 [ PartsList ]

Description 13 degree rotation of 1 domain relative to other

Particular values describing motion Experimental Methods = x (Traditional x-ray) Creation Date = 19970822 Modification Date = 19970822

References P J Baker, K L Britton, P C Engel, G W Farrants, K S Lilley, D W Rice, and T J Stillman (1992). Subunit Assembly and Active Site Location in the Structure of Glutamate Dehydrogenase. Proteins. 12:75-86. [Medline info for 95086863] T J Stillman, B J Baker, K L Britton and D W Rice (1993). Conformational Flexibility in Glutamate Dehydrogenase: Role of Water in Substrate Recognition and Catalysis. J. Mol. Biol. 234: 1131-1139. [Medline info for 95086863]

GO terms associated with structures Molecular function oxidoreductase activity Biological process amino acid metabolism

Morphs

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Best representative Morph Morph name Structure #1 Structure #2 Residues [ ] [ ]

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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu