Motion in Cell Adhesion Molecule CD2 [cd2]
[ jump to morphs ]
Classification Known Domain Motion, Hinge Mechanism [D-h-2]
Structures 1HNF Conformation 1 [ PartsList ] 1HNG Conformation 2 [ PartsList ]
Description 1 interdomain linkage, 1 hinge, 20 degree rotation. Comparison of rat and human forms reveals rotation between two Ig-like domain.
Particular values describing motion Experimental Methods = x (Traditional x-ray) Creation Date = 19970822 Modification Date = 19970822
References M J Bennet, M P Schlunegger, and D Eisenberg (1995). 3D Domain swapping: A Mechanism for oligomer assembly. Prot. Sci 4:2455-2468. [Medline info for 93250020] E Y Jones, S J Davis, A F Williams, K Harlos and D I Stuart (1992). Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2. Nature. 360: 232-239. [Medline info for 93063364] D L Bodian, E Y Jones, K Harlos, D I Stuart and S J Davis (1994). Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution. Structure. 2: 755-766. [Medline info for 95086863]
GO terms associated with structures Cellular component integral to membrane Biological process cell adhesion
Morphs
[ show all images ]
Best representative Morph Morph name Structure #1 Structure #2 Residues [ ] [ ]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu