Motion in Catabolite Gene Activator Protein (CAP) [cap]

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Classification Known Domain Motion, Hinge Mechanism [D-h-2]

Structures
1G6N Both forms
1GAP obsolete
3GAP obsolete [ PartsList ]

Description
1 interdomain linkage and 1 hinge. Comparison of subunits in the dimer reveals that the small domain has rotated ~30 degree closer to the large domain in one subunit. Motion is evident in comparing different subunits in the asymmetric unit. Single data bank identifier applies for both forms.

Particular values describing motion
Experimental Methods = x (Traditional x-ray)
Creation Date = 19970822
Modification Date = 19970822

References
I T Weber and T A Steitz (1987). Structure of a Complex of Catabolite Gene Activator Protein and Cyclic AMP Refined at 2.5 Å Resolution. J. Mol. Biol. 198: 311-326. [Medline info for 10074413]

GO terms associated with structures
Molecular functiontranscription factor activity
Cellular componentintracellular
Biological processregulation of transcription, DNA-dependent

Morphs

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Best representative
Morph Morph name Structure #1 Structure #2 Residues
Catabolite Gene Activator Protein upload [ A ] upload [ B ] 201



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Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu