Motion in Acetyl-CoA synthase [acs]
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Classification [D-h-2]
Structures 1OAO a2-B2 tetramer
Description Alpha subunits in the asymmetric unit have significantly different conformations of the three domains relative to eachother.
References Claudine Darnault, Anne Volbeda, Eun Jin Kim, Pierre Legrand, Xavier Vernède, Paul A Lindahl, Juan C Fontecilla-Camps (2003). Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] clusters in closed and open subunits of acetyl-CoA synthase/carbon monoxide dehydrogenase. Nat Struct Biol, 10:271-9 [Medline info for 12627225]
GO terms associated with structures Molecular function carbon-monoxide dehydrogenase (acceptor) activity, nickel ion binding, iron ion binding, oxidoreductase activity Cellular component cytoplasm Biological process generation of precursor metabolites and energy, acetyl-CoA metabolism, electron transport
Morphs
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Best representative Morph Morph name Structure #1 Structure #2 Residues [ ] [ ]
Copyright 1995-2005 M. Gerstein, W. Krebs, S. Flores, N. Echols, and others
Email: Mark.Gerstein _at_ yale.edu