Motion in Arabinose, Leucine, and Galactose Binding Proteins [abp]

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Classification Suspected Domain Motion, Hinge Mechanism [D-h-1]

1ABP Conformation 3
2GBP Conformation 2 [ PartsList ]
2LBP Conformation 1 [ PartsList ]

Similar to MBP and lactoferrin. However, these are group-I periplasmic binding proteins and are not as similar as group-II ones (above) are.

Particular values describing motion
Experimental Methods = x (Traditional x-ray)
Creation Date = 19970822
Modification Date = 19970822

J S Sack, M A Saper and F A Quiocho (1989a). Periplasmic Binding Protein Structure and Function: Refined X-ray structures of the Leucine/Isoleucine/Valine-binding Protein and its Complex with Leucine. J. Mol. Biol. 206: 171-191. [Medline info for 92395661]
J S Sack, S D Trakhanov, I H Tsigannik and F A Quiocho (1989b). Structure of the L-Leucine-binding Protein Refined at 2.4 Å Resolution and Comparison with the Leu/Ile/Val-binding Protein Structure. J. Mol. Biol. 206: 193-207. [Medline info for 92395661]
N K Vyas, M N Vyas and F A Quiocho (1991). Comparison of the periplasmic receptors for L-arabinose, D-glucose, and D-ribose structural and functional similarity. J. Biol. Chem. 266: 5226-5237. [Medline info for 92395661]
N K Vyas, M N Vyas and F A Quiocho (1988). Sugar and Signal-transducer Binding Sites of the Escherichia coli Galactose Chemoreceptor Protein. Science. 242: 1290. [Medline info for 92395661]
G L Gilliland and F A Quiocho (1981). Structure of the L-Arabinose-Binding Protein from Escherichia coli at 2.4 Å Resolution. J. Mol. Biol. 146: 341. [Medline info for 92395661]
Shilton BH, Flocco MM, Nilsson M, Mowbray SL (1996). Conformational changes of three periplasmic receptors for bacterial chemotaxis and transport: the maltose-, glucose/galactose- and ribose-binding proteins. J Mol Biol. 264(2):350-363. [Medline info for 97109101]

Data and Graphics
Graphic-1 Diagram of secondary structure.

GO terms associated with structures
Molecular functionamino acid-polyamine transporter activity
Cellular componentperiplasmic space (sensu Gram-negative Bacteria)
Biological processamino acid transport

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Email: Mark.Gerstein _at_